Alzheimer's disease is the most common form of dementia. The terms "Alzheimer's disease" and "dementia" are often used interchangeably, but they're not the same thing. Dementia is a general medical term to describe decline in memory and thinking severe enough to interfere with daily life. There are many different types of dementia; Alzheimer's is one example of a specific type.
In addition to memory loss, common symptoms of Alzheimer's include difficulty with familiar tasks, impaired judgment, and changes in mood and personality. For the majority of individuals, we do not know the exact reason the disease develops. Research has increased our knowledge about both genetic and non-genetic risk factors for Alzheimer's disease.
At this time, the strongest genetic clue we have in trying to better understand Alzheimer's disease is the APOE gene. Each of us has two copies of the APOE gene, one from Mom, and one from Dad.
There are 3 versions of the APOE gene. For short, we call these e2, e3 and e4. The e2 and e3 types of APOE are not risk factors for Alzheimer's disease. The e4 type of the APOE gene is a risk factor for Alzheimer's disease.
Along with participation from people like you, this study brings together some of the best and brightest organizations in the Alzheimer's community:
The study is sponsored by Novartis, a Swiss pharmaceutical company, and Amgen, a biotechnology company based in Thousand Oaks, CA, in collaboration with BAI, with funding from the National Institute on Aging, part of the National Institutes of Health (NIH), as well as the Alzheimer’s Association, FBRI, GHR Foundation and Banner Alzheimer’s Foundation.